Anti-Mouse CD8a In Vivo Antibody - Ultra Low Endotoxin (2.43)

Anti-Mouse CD8a In Vivo Antibody - Ultra Low Endotoxin (2.43)

Catalog Number:
A001437609ICH
Mfr. No.:
ICH1045UL
Price:
$832
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      • Overview
        • Antigen Distribution: CD8a (Ly 2.2) is present on the surface of most thymocytes and a subpopulation of mature T-lymphocytes which include most T suppressor/cytotoxic-cells. CD8 participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck.
          Specificity: Anti-CD8a In Vivo Antibody - Ultra Low Endotoxin (2.43) recognizes an epitope on Mouse CD8a
          Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
          Isotype Control: Rat IgG2b In Vivo Isotype Control - Ultra Low Endotoxin [1-2] (ICH2243UL)
          Endotoxin: ≤ 0.75 EU/mg as determined by the LAL method
          Aggregation: Aggregation level ≤ 1%

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      • Properties
        • Host
          rat
          Isotype
          IgG2b
          Reactivity
          mouse
          Clone
          2.43
          Purification
          >98% by SDS-PAGE and HPLC
          Formulation
          This purified antibody is formulated with no carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl.
          Storage
          anti-CD8a In Vivo Antibody - Ultra Low Endotoxin (2.43) is stable when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 80°C. Avoid Repeated Freeze Thaw Cycles.
          Molecular Weight
          1.0 - 5.0 mg/ml
          Regulatory Status
          Functional Assay: In vivo Depletion: It has been reported that Balb/C mice may be injected intraperitoneally with 1.0 mg of Rat Anti-Mouse CD8a (Clone 2.43) antibody and allowed to rest for 24 hours for CD8+ T cell depletion.
          Antigen

          * Products are for research use only. Not for use in diagnostic or therapeutic procedures.

      • Applications
        • Application
          Immunoprecipitation; WB; Flow Cytometry; Immunofluorescence; Functional Assays

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