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Overview
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MART‐1 (Melanoma Antigen Recognized by T cells 1) or Melan‐A1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. MART‐1 is present in melanosomes and endoplasmic reticulum. Clone 103 does not cross‐react with MAGE‐1 or tyrosinase protein. Clone 103 labels melanomas and other tumors showing melanocytic differentiation. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
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