Name: Anti-MED1 antibody
Price: 297.00 USD

Overview
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e. g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MED1 (NP_004765. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Mediator Of Rna Polymerase II Transcription Subunit 1; Activator-Recruited Cofactor 205 Kda Component; Arc205; Mediator Complex Subunit 1; Peroxisome Proliferator-Activated Receptor-Binding Protein; Pbp; Ppar-Binding Protein; Thyroid Hormone Receptor-Associated Protein Complex 220 Kda Component; Trap220; Thyroid Receptor-Interacting Protein 2; Tr-Interacting Protein 2; Trip-2; Vitamin D Receptor-Interacting Protein Complex Component Drip205; P53 Regulatory Protein Rb18a (Gene ID:5469; UniProt:Q15648)
  
  * For research use only