Anti-LAIR1 antibody

Anti-LAIR1 antibody

Catalog Number:
A001019921STJ
Mfr. No.:
STJ112159
Price:
$297
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      • Overview
        • The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13. 4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant protein of human LAIR1
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Leukocyte-Associated Immunoglobulin-Like Receptor 1; Lair-1; Hlair1; Cd Antigen Cd305 (Gene ID:3903; UniProt:Q6GTX8)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:1000-1:4000

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