Anti-Ki67 antibody

Anti-Ki67 antibody

Catalog Number:
A001049202STJ
Mfr. No.:
STJ93832
Price:
$224
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      • Overview
        • Ki67 is a protein encoded by the MKI67 gene which is approximately 358, 6 kDa. Ki67 is localised to the nucleus. It is involved in DNA damage and neuroscience. It is a nuclear protein that is associated with and may be necessary for cellular proliferation. It is required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. It also associates with the surface of the mitotic chromosome, the peri-chromosomal layer, and covers a substantial fraction of the chromosome surface. Ki67 is expressed preferentially during late G1, S, G2 and M phases of the cell cycle. Mutations in the MKI67 gene may result in brain ependymoma and amyloplastic carcinoma. STJ93832 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Ki-67 protein.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Synthesized peptide derived from human Ki-67
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Proliferation Marker Protein Ki-67; Antigen Identified By Monoclonal Antibody Ki-67; Antigen Ki-67; Antigen Ki67 (Gene ID:4288; UniProt:P46013)

          * For research use only

      • Applications
        • Application
          WB; IHC (paraffin); IF; ELISA
        • Application Dilutions
          IHC 1:100-1:300
          IF 1:200-1:1000
          ELISA 1:20000

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