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Overview
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The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin-2, -4, -7 and-21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
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- Properties
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Overview