Name: Anti-IGF2BP3 antibody
Price: 392.00 USD

Overview
- Insulin‐like growth factor II mRNA binding protein 3 (IMP3) is an oncofetal RNA‐binding protein that regulates targets such as insulin‐like growth factor‐2 and beta‐actin. IMP3 plays a major role in early embryogenesis involving the development of the intestine, thymus, pancreas, and kidneys. IMP3 mRNA transcript and protein have been demonstrated in high levels in pancreatic cancer tissues but not in benign lesions of the pancreas, chronic pancreatitis, or normal pancreatic tissues. IMP3 can be used to distinguish between pancreatic ductal adenocarcinoma from chronic sclerosing pancreatitis. IMP3 expression has also been found in a variety of other human cancers including renal cell carcinoma, adenocarcinoma of the uterine cervix, endometrial carcinoma, adenocarcinoma of the esophagus, malignant melanoma, Merkel cell carcinoma, urothelial carcinoma, neuroendocrine carcinoma of the lung, adenocarcinoma of the pancreas, and triple negative breast cancer.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Clone
  
  EP286
  
  Immunogen
  
  Recombinant fragment within Human IMP3
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Purified antibody diluted in Tris‐HCI buffer containing stabilizing protein and <0.1% sodium azide.
  
  Storage
  
  Store at 2-8°C for up to 1 year
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Signal Peptide Peptidase-Like 2a; Spp-Like 2a; Sppl2a; Intramembrane Protease 3; Imp-3; Presenilin-Like Protein 2 (Gene ID:84888; UniProt:Q8TCT8)
  
  * For research use only