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Overview
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Background
CD37 is a 40-52 kD type II transmembrane protein, also known as tetraspanin-26. It is a member of the transmembrane tetraspanin family. It can interact with integrins and other transmembrane 4 superfamily members (CD53, CD81, CD82). CD37 is expressed predominantly on B cells; low expression is detected on T cells and myeloid cells. No expression is reported on NK cells and plasma cells. It is involved in regulation of T cell proliferation.
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