Name: Anti-Human CD20 Monoclonal Antibody ( AF647 Conjugated )
Price: 268.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
- Properties
  - Host
    
    mouse
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG2a kappa
    
    Reactivity
    
    human
    
    Conjugate
    
    Alexa-fluor®-647
    
    Formulation
    
    PBS with 0.05% Proclin300, 1% BSA
    
    Storage
    
    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
    
    Antigen
    
    B-lymphocyte antigen CD20; MS4A1; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; MS4A1; CD20 (Gene ID:931; UniProt:P11836)
    
    * For research use only.
- Applications
  - Application
    
    Flow Cytometry