Name: Anti-HSD17B10 antibody
Price: 297.00 USD

Overview
- This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17 beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human HSD17B10 (NP_004484. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  3-Hydroxyacyl-Coa Dehydrogenase Type-2; 17-Beta-Hydroxysteroid Dehydrogenase 10; 17-Beta-Hsd 10; 2-Methyl-3-Hydroxybutyryl-Coa Dehydrogenase; Mhbd; 3-Hydroxy-2-Methylbutyryl-Coa Dehydrogenase; 3-Hydroxyacyl-Coa Dehydrogenase Type II; Endoplasmic Reticulum-Associated Amyloid Beta-Peptide-Binding Protein; Mitochondrial Ribonuclease P Protein 2; Mitochondrial Rnase P Protein 2; Short Chain Dehydrogenase/Reductase Family 5c Member 1; Short-Chain Type Dehydrogenase/Reductase Xh98g2; Type II Hadh (Gene ID:3028; UniProt:Q99714)
  
  * For research use only