Name: Anti-HIF1a antibody
Price: 304.00 USD

Overview
- Goat polyclonal to alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in apoptosis, angiogenesis, energy metabolism, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in tumour angiogenesis, embryonic vascularization, and pathophysiology of ischemic disease.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  goat
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  avian; bovine; canine; donkey; feline; goat; guinea pig; hamster; horse; human; mouse; porcine; rabbit; rat; sheep; simian
  
  Immunogen
  
  Recombinant peptide derived from within residues 470 to 590 aa of human HIF1a produced in E. coli.
  
  Purification
  
  This antibody is epitope-affinity purified from goat antiserum.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS, 20% glycerol and 0.05% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeated freeze-thaw cycles.
  
  Concentration
  
  3 mg/mL
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8) (Gene ID:3091)
  
  * For research use only