Anti-HDAC1 antibody

Anti-HDAC1 antibody

Catalog Number:
A001053090STJ
Mfr. No.:
STJ97722
Price:
$224
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      • Overview
        • HDAC1 is a protein encoded by the HDAC1 gene which is approximately 55, 1 kDa. HDAC1is localised to the nucleus. It is involved in notch signalling pathways and p53 signalling. This protein falls under the histone deacetylase family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation plays a key role in the regulation of eukaryotic gene expression. It also interacts with a retinoblastoma tumour-suppressor protein which forms a complex that is key in controlling cell proliferation and differentiation. HDAC1 is ubiquitously expressed with higher levels in heart, pancreas and testis. Mutations in the HDAC1 gene may result in Rett syndrome. STJ97722 was developed from clone 4E1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of HDAC1.

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1
          Reactivity
          human; rat; mouse
          Clone
          4E1
          Immunogen
          synthetic peptide derived from HDAC1
          Purification
          The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Histone Deacetylase 1; Hd1 (Gene ID:3065; UniProt:Q13547)

          * For research use only

      • Applications
        • Application
          IF; IHC (paraffin)
        • Application Dilutions
          IF 1:50-200
          IHC 1:100-200

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