Name: Anti-HCFC1 antibody
Price: 297.00 USD

Overview
- This gene is a member of the host cell factor family and encodes a protein with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N-and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human HCFC1 (NP_005325. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Host Cell Factor 1; Hcf; Hcf-1; C1 Factor; Cff; Vcaf; Vp16 Accessory Protein Cleaved Into-Hcf N-Terminal Chain 1-Hcf N-Terminal Chain 2-Hcf N-Terminal Chain 3-Hcf N-Terminal Chain 4-Hcf N-Terminal Chain 5-Hcf N-Terminal Chain 6-Hcf C-Terminal Chain 1-Hcf C-Terminal Chain 2-Hcf C-Terminal Chain 3-Hcf C-Terminal Chain 4-Hcf C-Terminal Chain 5-Hcf C-Terminal Chain 6 (Gene ID:3054; UniProt:P51610)
  
  * For research use only