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Overview
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Glut1 is a protein encoded by the SLC2A1 gene which is approximately 54 kDa. Glut1 is localised to the cell membrane. It is involved in the transport of glucose, bile salts, organic acids, metal ions and amine compounds, the metabolism of water-soluble vitamins and cofactors, and hexose transport. It is a glucose transporter that enables the movement of glucose across the cell membrane. Glucose is an essential source of energy for mammalian cells, and is also used as a substrate in protein and lipid synthesis. Glut1 is expressed in the nervous system, liver, kidney, intestine and skin. Mutations in the SLC2A1 gene may result in dystonia and Glut1 deficiency syndrome. STJ93293 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Glut1 protein.
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Overview