Anti-GARS antibody

Anti-GARS antibody

Catalog Number:
A001035849STJ
Mfr. No.:
STJ27388
Price:
$295
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      • Overview
        • This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 60-370 of human GARS (NP_002038. 2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Glycine--Trna Ligase; Diadenosine Tetraphosphate Synthetase; Ap4a Synthetase; Glycyl-Trna Synthetase; Glyrs; Glycyl-Trna Synthetase 1 (Gene ID:2617; UniProt:P41250)

          * For research use only

      • Applications
        • Application
          WB; IHC
        • Application Dilutions
          WB 1:1000-1:4000
          IHC 1:50-1:200

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