Anti-GABRA4 antibody

Anti-GABRA4 antibody

Catalog Number:
A001033964STJ
Mfr. No.:
STJ23730
Price:
$297
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      • Overview
        • Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 36-258 of human GABRA4 (NP_000800. 2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Gamma-Aminobutyric Acid Receptor Subunit Alpha-4; Gaba(A Receptor Subunit Alpha-4 (Gene ID:2557; UniProt:P48169)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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