Name: Anti-FASLG antibody
Price: 297.00 USD

Overview
- This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FasLG (NP_000630. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Tumor Necrosis Factor Ligand Superfamily Member 6; Apoptosis Antigen Ligand; Aptl; Cd95 Ligand; Cd95-L; Fas Antigen Ligand; Fas Ligand; Fasl; Cd Antigen Cd178 Cleaved Into-Tumor Necrosis Factor Ligand Superfamily Member 6-Membrane Form-Tumor Necrosis Factor Ligand Superfamily Member 6-Soluble Form; Receptor-Binding Fasl Ectodomain; Soluble Fas Ligand; Sfasl-Adam10-Processed Fasl Form; Apl-Fasl Intracellular Domain; Fasl Icd; Sppl2a-Processed Fasl Form; Spa (Gene ID:356; UniProt:P48023)
  
  * For research use only