Anti-ERVFRD-1 antibody

Anti-ERVFRD-1 antibody

Catalog Number:
A001019963STJ
Mfr. No.:
STJ112201
Price:
$297
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      • Overview
        • Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 16-250 of human ERVFRD-1 (NP_997465. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Syncytin-2; Endogenous Retrovirus Group Frd Member 1; Envelope Polyprotein; Herv-Frd; Herv-Frd_6p24.1 Provirus Ancestral Env Polyprotein Cleaved Into-Surface Protein; Su-Transmembrane Protein; Tm (Gene ID:405754; UniProt:P60508)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:1000-1:4000

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