Name: Anti-ERCC2 antibody
Price: 297.00 USD

Overview
- The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ERCC2 (NP_001124339. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  General Transcription And Dna Repair Factor IIh Helicase Subunit Xpd; TfIIh Subunit Xpd; Basic Transcription Factor 2 80 Kda Subunit; Btf2 P80; Cxpd; Dna Excision Repair Protein Ercc-2; Dna Repair Protein Complementing Xp-D Cells; TfIIh Basal Transcription Factor Complex 80 Kda Subunit; TfIIh 80 Kda Subunit; TfIIh P80; Xeroderma Pigmentosum Group D-Complementing Protein (Gene ID:2068; UniProt:P18074)
  
  * For research use only