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Overview
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Ephrin-A3 is a protein encoded by the EFNA3 gene which is approximately 26, 3 kDa. Ephrin-A3 is localised to the cell membrane. It is involved in EPHA forward signalling, the Ras signalling pathway, developmental biology and axon guidance. The ephrins make up the largest subfamily of receptor protein-tyrosine kinases, they are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-A3 is expressed in brain, skeletal muscle, thymus, prostate, testis, ovary, and peripheral blood leukocytes. Mutations in the EFNA3 gene may result in Androgenic Alopecia. STJ92956 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Ephrin-A3 protein.
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