Anti-EIF4G3 antibody

Anti-EIF4G3 antibody

Catalog Number:
A001023680STJ
Mfr. No.:
STJ116828
Price:
$297
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      • Overview
        • The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1200 of human EIF4G3 (NP_003751. 2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Eukaryotic Translation Initiation Factor 4 Gamma 3; Eif-4-Gamma 3; Eif-4g 3; Eif4g 3; Eif-4-Gamma II; Eif4gII (Gene ID:8672; UniProt:O43432)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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