Name: Anti-DDR1 antibody
Price: 297.00 USD

Overview
- Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 290-420 of human DDR1 (NP_054700. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Epithelial Discoidin Domain-Containing Receptor 1; Epithelial Discoidin Domain Receptor 1; Cd167 Antigen-Like Family Member A; Cell Adhesion Kinase; Discoidin Receptor Tyrosine Kinase; Hgk2; Mammary Carcinoma Kinase 10; Mck-10; Protein-Tyrosine Kinase 3a; Protein-Tyrosine Kinase Rtk-6; Trk E; Tyrosine Kinase Ddr; Tyrosine-Protein Kinase Cak; Cd Antigen Cd167a (Gene ID:780; UniProt:Q08345)
  
  * For research use only