Anti-CYP7B1 antibody

Anti-CYP7B1 antibody

Catalog Number:
A001026610STJ
Mfr. No.:
STJ119883
Price:
$297
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      • Overview
        • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CYP7B1 (NP_004811. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Cytochrome P450 7b1; 24-Hydroxycholesterol 7-Alpha-Hydroxylase; 25/26-Hydroxycholesterol 7-Alpha-Hydroxylase; 3-Hydroxysteroid 7-Alpha Hydroxylase; Oxysterol 7-Alpha-Hydroxylase (Gene ID:9420; UniProt:O75881)

          * For research use only

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:1000

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