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Overview
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Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. Primary function of IL-8 is the induction of chemotaxis in its target cells (e.g. neutrophil granulocytes). It serves as a chemical signal that attracts neutrophils at the site of inflammation. IL-8 is a promising marker for many clinical conditions and currently being applied by various subspecialties of medicine either for the purpose of rapid diagnosis or as a predictor of prognosis. IL-8 level increases as a result of many inflammatory conditions, so careful interpretation of IL-8 level is required to make correlation with desired clinical condition's diagnosis or prognosis.
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