Name: Anti-Collagen I antibody
Price: 224.00 USD

Overview
- Collagen I is a protein encoded by the COL1A1 gene which is approximately 138, 9 kDa. Collagen I is secreted into the extracellular space. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling, focal adhesion and the phospholipase-C pathway. It is a pro-alpha-1 chain of type I collagen whose triple helix comprises two alpha-1 chains and one alpha-2 chain. Collagen I is expressed in the bone, skin, eye, lung and nervous system. Mutations in the COL1A1 gene may result in Caffey disease and Ehlers-Danlos syndrome. STJ98915 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous Collagen I protein.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  synthetic peptide derived from Collagen I.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Collagen Alpha-1(I Chain; Alpha-1 Type I Collagen (Gene ID:1277; UniProt:P02452)
  
  * For research use only

Applications

Application

IF; IHC (paraffin)

Application	Dilutions
IF	1:50-200
WB	500-2000
IHC (paraffin)	1:50-300

Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-Collagen I antibody

Anti-Collagen I antibody

Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human skin. 1, Antibody was diluted at 1:200 (4°C overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-Collagen I antibody

Anti-Collagen I antibody

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