Anti-CEP290 antibody

Anti-CEP290 antibody

Catalog Number:
A001047595STJ
Mfr. No.:
STJ92224
Price:
$224
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      • Overview
        • CEP290 is a protein encoded by the CEP290 gene which is approximately 290, 3 kDa. CEP290 is localised to the cytoplasm. It is involved in regulation of PLK1 activity at G2/M transition, innate immune system and mitotic cell cycle. It is a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. It is involved in the early and late steps of cilia formation. CEP290 is ubiquitously expressed with stronger expression in the placenta. Mutations in the CEP290 gene may result in Joubert syndrome. STJ92224 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CEP290 protein.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Synthesized peptide derived from human CEP290
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Centrosomal Protein Of 290 Kda; Cep290; Bardet-Biedl Syndrome 14 Protein; Cancer/Testis Antigen 87; Ct87; Nephrocystin-6; Tumor Antigen Se2-2 (Gene ID:80184; UniProt:O15078)

          * For research use only

      • Applications
        • Application
          WB; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          ELISA 1:20000

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