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Overview
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C/EBP beta is a protein encoded by the CEBPB gene which is approximately 36, 1 kDa. C/EBP beta is localised to the nucleus and cytoplasm. It is involved in IL-17 family signalling pathways, cellular senescence, human embryonic stem cell pluripotency and the IL-2 pathway. It functions as a homodimer but can also form heterodimers with enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. C/EBP beta is expressed at low levels in the lung, kidney and spleen. Mutations in the CEBPB gene may result in myxoid liposarcoma and leukaemia. STJ91918 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of C/EBP beta protein.
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Overview