Anti-C/EBP Beta antibody

Anti-C/EBP Beta antibody

Catalog Number:
A001047289STJ
Mfr. No.:
STJ91918
Price:
$224
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      • Overview
        • C/EBP beta is a protein encoded by the CEBPB gene which is approximately 36, 1 kDa. C/EBP beta is localised to the nucleus and cytoplasm. It is involved in IL-17 family signalling pathways, cellular senescence, human embryonic stem cell pluripotency and the IL-2 pathway. It functions as a homodimer but can also form heterodimers with enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. C/EBP beta is expressed at low levels in the lung, kidney and spleen. Mutations in the CEBPB gene may result in myxoid liposarcoma and leukaemia. STJ91918 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of C/EBP beta protein.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthesized peptide derived from human C/EBP beta around the non-phosphorylation site of T235.
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Ccaat/Enhancer-Binding Protein Beta; C/Ebp Beta; Liver Activator Protein; Lap; Liver-Enriched Inhibitory Protein; Lip; Nuclear Factor Nf-Il6; Transcription Factor 5; Tcf-5 (Gene ID:1051; UniProt:P17676)

          * For research use only

      • Applications
        • Application
          IF; WB; IHC (paraffin); ELISA
        • Application Dilutions
          IF 1:50-200
          WB 1:500-1:2000
          IHC 1:100-1:300
          ELISA 1:10000

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