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Overview
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Cdk2 is a protein encoded by the CDK2 gene which is approximately 33, 9 kDa. Cdk2 is localised to the cytoplasm and nucleus. It is involved in CDK-mediated phosphorylation and removal of Cdc6, DNA double-strand break repair and cell cycle regulation. It is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle, it is especially critical during the G1 to S phase transition. Cdk2 is expressed in skin, intestine, nervous system, lung and liver. Mutations in the CDK2 gene may result in glioblastoma and retinal cancer. STJ92197 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Cdk2 protein.
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