Anti-CD7 antibody

Anti-CD7 antibody

Catalog Number:
IGA1028173STJ
Mfr. No.:
STJ16100342
Price:
$1,649
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      • Overview
        • CD7 antigen is a 40-kDa cell surface glycoprotein that is a member of the immunoglobulin genesuperfamily. While its precise function is not known, it is suggested that CD7 plays a role in T-cellinteractions as it is one of the earliest T-cell lineage associated antigens expressed during T-cellontogeny. CD7 is expressed in thymocytes, mature peripheral T-cells, natural killer cells, and lymphoidand myeloid progenitors. CD7 is the most consistently expressed T cell antigen in lymphoblasticlymphomas and leukemias, and is therefore a useful marker in the identification of such neoplasticproliferations. In mature post-thymic T cell neoplasms, it is the most common pan-T antigen to beaberrantly absent and its absence in a T cell population is a useful pointer to a neoplastic conversion.

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      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG1 kappa
          Reactivity
          human
          Clone
          MRQ-56
          Conjugate
          Unconjugated
          Formulation
          1 ml supernatant in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
          Storage
          Store antibody at 2-8°C until expiry date. Minimise freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          T-Cell Antigen Cd7; Gp40; T-Cell Leukemia Antigen; T-Cell Surface Antigen Leu-9; Tp41; Cd Antigen Cd7 (Gene ID:924; UniProt:P09564)

          * For research use only

      • Applications
        • Application
          IHC (paraffin)
        • Application Dilutions
          IHC 1: 100 – 1:500

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