Name: Anti-CCR7 antibody
Price: 297.00 USD

Overview
- The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse
  
  Immunogen
  
  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR7 (NP_001829. 1).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  C-C Chemokine Receptor Type 7; C-C Ckr-7; Cc-Ckr-7; Ccr-7; Blr2; Cdw197; Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1; Ebi1; Ebv-Induced G-Protein Coupled Receptor 1; Mip-3 Beta Receptor; Cd Antigen Cd197 (Gene ID:1236; UniProt:P32248)
  
  * For research use only