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Overview
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Catalase is a protein encoded by the CAT gene which is approximately 59, 7 kDa. Catalase is localised to the peroxisome. It is involved in detoxification of reactive oxygen species, the innate immune system, purine metabolism and longevity regulating pathway. It acts as a key antioxidant enzyme in the bodies defence against oxidative stress. It converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Catalase is expressed in the liver, cells of the nervous system, blood, kidney and eye. Mutations in the CAT gene may result in Refsum disease. STJ96520 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Catalase protein.
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