Anti-CaMKI Beta/gamma antibody

Anti-CaMKI Beta/gamma antibody

Catalog Number:
A001047361STJ
Mfr. No.:
STJ91990
Price:
$224
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      • Overview
        • CaMKII beta/gamma is a protein encoded by the CAMK2G gene which is approximately 62, 6 kDa. CaMKII beta/gamma is localised to the sarcoplasmic reticulum membrane. It is involved in RET signalling, post NMDA receptor activation events, development angiotensin activation of ERK and cardiac conduction. It is a calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation. It is also involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. CaMKII beta/gamma is expressed in skeletal muscle. Mutations in the CAMK2G gene may result in Timothy syndrome and exudative vitreoretinopathy. STJ91990 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CaMKII beta/gamma protein.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Synthesized peptide derived from human CaMKIIbeta/gamma
          Purification
          The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
          Conjugate
          Unconjugated
          Formulation
          Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
          Storage
          Store at -20°C and avoid repeat freeze-thaw cycles.
          Concentration
          1 mg/ml
          Regulatory Status
          RUO
          Antigen
          Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Beta; Cam Kinase II Subunit Beta; Camk-II Subunit Beta (Gene ID:818; UniProt:Q13555)

          * For research use only

      • Applications
        • Application
          WB; IF; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IF 1:200-1:1000
          ELISA 1:20000

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