Name: Anti-c-Fos antibody
Price: 224.00 USD

Overview
- c-Fos is a protein encoded by the FOS gene which is approximately 40, 6 kDa. c-Fos is localised to the nucleus, endoplasmic reticulum and cytoplasm. It is involved in activated TLR4 signalling, theIL-2 pathway and toll-like receptor signalling pathways. It is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton. c-Fos is expressed at low levels in quiescent cells. Mutations in the FOS gene may result in cerebral hypoxia and myositis ossificans. STJ92252 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of c-Fos protein.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human; mouse; rat
  
  Immunogen
  
  Synthesized peptide derived from human c-Fos around the non-phosphorylation site of S374.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Proto-Oncogene C-Fos; Cellular Oncogene Fos; G0/G1 Switch Regulatory Protein 7 (Gene ID:2353; UniProt:P01100)
  
  * For research use only