Anti-ATP7B antibody

Anti-ATP7B antibody

Catalog Number:
A001036042STJ
Mfr. No.:
STJ27643
Price:
$297
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      • Overview
        • This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 1055-1354 of human ATP7B (NP_001230111. 1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Copper-Transporting Atpase 2; Copper Pump 2; Wilson Disease-Associated Protein Cleaved Into-Wnd/140 Kda (Gene ID:540; UniProt:P35670)

          * For research use only

      • Applications
        • Application
          WB; IF
        • Application Dilutions
          WB 1:500-1:2000
          IF 1:50-1:200

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