Name: Anti-ATIC antibody
Price: 297.00 USD

Overview
- This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
  
  Please contact us at for specific academic pricing.
Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ATIC (NP_004035. 2).
  
  Purification
  
  Affinity purification
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  
  Storage
  
  Store at -20°C and avoid freeze-thaw cycles.
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Bifunctional Purine Biosynthesis Protein Purh Cleaved Into-Bifunctional Purine Biosynthesis Protein Purh-N-Terminally Processed Includes-Phosphoribosylaminoimidazolecarboxamide Formyltransferase; 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase; Aicar Transformylase-Imp Cyclohydrolase; Atic; Imp Synthase; Inosinicase (Gene ID:471; UniProt:P31939)
  
  * For research use only