Name: Anti-alpha-tubulin (Acetyl Lys40) antibody
Price: 224.00 USD

Overview
- Tubulin alpha is a protein encoded by the TUBA1A gene which is approximately 50, 1 kDa. Tubulin alpha is localised to the cytoplasm. It is involved in the regulation of PLK1 activity at G2/M transition, development Slit-Robo signalling, the mitotic cell cycle and chaperonin-mediated protein folding. This protein falls under the tubulin family. Tubulin is the major constituent of microtubules which perform essential and diverse functions within the eukaryotic cytoskeleton. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Tubulin alpha is expressed at high levels in the foetal brain. Mutations in the TUBA1A gene may result in lissencephaly. STJ97537 was developed from clone 4A8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous tubulin alpha proteins.
  
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Properties
- Host
  
  mouse
  
  Antibody Type
  
  monoclonal
  
  Isotype
  
  IgG1
  
  Reactivity
  
  human; rat; mouse
  
  Clone
  
  4A8
  
  Immunogen
  
  Synthetic Peptide
  
  Purification
  
  The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Tubulin Alpha-1b Chain; Alpha-Tubulin Ubiquitous; Tubulin K-Alpha-1; Tubulin Alpha-Ubiquitous Chain [Cleaved Into-Detyrosinated Tubulin Alpha-1b Chain] (Gene ID:7277; UniProt:P68363)
  
  * For research use only