Anti-ADRBK1 antibody

Anti-ADRBK1 antibody

Catalog Number:
A001033264STJ
Mfr. No.:
STJ22534
Price:
$295
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      • Overview
        • The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

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      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human ADRBK1 (NP_001610. 2).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
          Storage
          Store at -20°C and avoid freeze-thaw cycles.
          Regulatory Status
          RUO
          Antigen
          Beta-Adrenergic Receptor Kinase 1; Beta-Ark-1; G-Protein Coupled Receptor Kinase 2 (Gene ID:156; UniProt:P25098)

          * For research use only

      • Applications
        • Application
          WB; IHC
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:50-1:200

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