Name: Anti-ABCG2 antibody
Price: 224.00 USD

Overview
- ABCG2 is a protein encoded by the ABCG2 gene which is approximately 72, 3 kDa. ABCG2 is localised to the cell membrane and mitochondrion membrane. It is involved in the Gefitinib pathway, Irinotecan pathway, and pyrimidine metabolism. It is a high-capacity urate exporter functioning in both renal and extrarenal urate excretion. It plays a role in porphyrin homeostasis as it is able to mediate the export of protoporhyrin IX both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. ABCG2 is highly expressed in the placenta. Mutations in the ABCG2 gene may result in erythroplakia and hyperuricemia. STJ97253 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ABCG2 protein.
  
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Properties
- Host
  
  rabbit
  
  Antibody Type
  
  polyclonal
  
  Isotype
  
  IgG
  
  Reactivity
  
  human
  
  Immunogen
  
  Synthesized peptide derived from human ABCG2.
  
  Purification
  
  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  
  Conjugate
  
  Unconjugated
  
  Formulation
  
  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  
  Storage
  
  Store at -20°C and avoid repeat freeze-thaw cycles.
  
  Concentration
  
  1 mg/ml
  
  Regulatory Status
  
  RUO
  
  Antigen
  
  Broad Substrate Specificity Atp-Binding Cassette Transporter Abcg2; Atp-Binding Cassette Sub-Family G Member 2; Breast Cancer Resistance Protein; Cdw338; Mitoxantrone Resistance-Associated Protein; Placenta-Specific Atp-Binding Cassette Transporter; Urate Exporter; Cd Antigen Cd338 (Gene ID:9429; UniProt:Q9UNQ0)
  
  * For research use only