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Overview
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Calculated MW: 10kDa/14kDa/17kDa/21kDa/22kDa
Observed MW: 38kDaPlease contact us at for specific academic pricing.
Background
Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
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