Name: Angiotensin 1/2 (1-7) amide
Price: 164.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Angiotensin I/II (1-7) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide) is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse.
    Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe | His-Leu) is an octapeptide that is converted from Angiotensin I (AI) through the removal of two C-terminal residues by angiotensin-converting enzyme (ACE), primarily by ACE within the lung (but also those present in endothelial and kidney epithelial cells). Ang-(1–7) is an endogenous peptide fragment that can be produced from Ang I or Ang II via endo- or carboxy-peptidases respectively. [1]
    Angiotensin I/II (1-7) amide is an amide derivative of angiotensin II that is a powerful vasoconstrictor and vasopressor, and is used in the treatment of certain hypotensive states. Angiotensin I/II (1-7) amide is usually administered by slow intravenous infusion, and sometimes intramuscularly or subcutaneously.
    
    1. Santos et al (2000) Angiotensin-(1-7): an update. Regul.Pept. 91 45.
- Properties
  - Categories
    
    Vasoconstrictor
    
    Alternative Name
    
    H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide
    
    Molecular Formula
    
    C41H63N13O10
    
    Molecular Weight
    
    898.02
    
    Appearance
    
    A solid
    
    Purity
    
    99.23%
    
    Solubility
    
    insoluble in EtOH; ≥12.1 mg/mL in H2O; ≥89.8 mg/mL in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    O=C(N)[[email protected]@H]1N(C([[email protected]@H](NC([[email protected]@H](NC([[email protected]@H](NC([[email protected]@H](NC([[email protected]@H](NC(CNC)=O)CCCNC(N)=N)=O)C)=O)CC2=CC=C(O)C=C2)=O)[[email protected]@H](C)CC)=O)CC3=CNC=N3)=O)CCC1
    
    * For Research Use Only