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Overview
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Amino functionalized methoxyl polyethylene glycol, amino PEG (mPEG-NH2) is a mono reactive PEG derivative that can be used to modify proteins, peptides and other materials via carboxylic group (-COOH) or other amine reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Application: Methoxypolyethylene glycol amine can: Form dendritic micelles to enhance the solubility of hydrophobic compounds.Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.Please contact us at for specific academic pricing.
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Overview
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