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Overview
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Polyethyleneglycols (PEGs) are widely used for material modifications to improve hydrophilicity of the surface. PEG-coated materials are usually more stable under physiological conditions. Since Amino-EG6-undecanethiol has 6 ethylene glycol units, 11 carbon atoms, and an SH group at the end, it can be used to prepare a highly oriented and hydrophilic SAM on a gold surface. This is suitable for biomaterial labeling on the surface due to the improved hydrophilicity. The hydrophilic surface can prevent proteins or other biomaterials from non-specific binding. Therefore, the SAM prepared by this reagent will provide a better surface to develop biomaterial sensors or DNA/ protein microarrays. To prepare an Amino-EG6-SAM on a gold surface, hydroxy-EGn-undecanethiols (n=3, 6) are used to dilute the number of amino groups according to the density of the molecules being introduced onto the surface.
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- Properties
- Applications
- Reference
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Overview