Ames Assay Kit

The bacterial reverse mutation test, also known as the Ames Assay, is commonly employed as an initial screen for genotoxic activity and, in particular, for point mutation-inducing activity. It detects mutations which revert mutations present in the test strains and restore the functional capability of the bacteria to synthesize an essential amino acid (histidine for Salmonella typhimurium or tryptophan for Escherichia coli). At least five strains of bacteria should be used, including of S. typhimurium strains (such as TA98, TA100, TA1535, and TA1537) and E.coli strain to detect point mutations of substitution, addition or deletion of DNA base pairs.

Please contact us at for specific academic pricing.