α-Amanitin

α-Amanitin

Catalog Number:
L002369297APE
Mfr. No.:
APE-A4548
Price:
$406
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          α-Amanitin, the most deleterious toxin of A. phalloides to humans, inhibits RNA polymerase II (RNAPII), causing hepatic and renal failure.

      • Properties
        • CAS Number
          23109-05-9
          Molecular Formula
          C39H54N10O14S
          Molecular Weight
          918.97
          Appearance
          A solid
          Purity
          98.00%
          Solubility
          ≥1 mg/mL in H2O; Soluble in Ethanol
          Storage
          Store at -20°C

          * For Research Use Only

      • Reference
        • 1. Jiangli Lang, Chen Yang, et al. "High Glucose Activates ERK1/2 to Stabilize AP1 and Increase MMP9 Expression in Diabetic Foot Ulcers." Exp Cell Res. 2021 Mar 3;112550. PMID:33675806
          2. Huo X, Ji L, et al. "The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation." Mol Cell. 2019 Oct 28. pii: S1097-2765(19)30761-0. PMID:31677973

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