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AM 251

AM 251

Catalog Number:
L002234127BIO
Mfr. No.:
BA17338
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      • Overview

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      • Properties
        • Categories
          Ligands of GPCRs
          Alternative Name
          1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
          CAS Number
          183232-66-8
          Molecular Formula
          C22H21Cl2IN4O
          Molecular Weight
          555.24 g/mol
          MDL Number
          MFCD01861181
          Note
          There is no hazardous surcharge associated with this product.
          There is no special packaging charge associated with this product.

          * For research use only. Not for human or veterinary use

      • Reference

        • Xi et al (2006). Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. The Journal of Neuroscience. 26(33):8531-6.
          Chambers et al (2004). Cannabinoid (CB)1 receptor antagonist, AM 251, causes a sustained reduction of daily food intake in the rat. Physiology & Behavior. 82(5):863-9.
          Fiori et al (2011). The cannabinoid receptor inverse agonist AM251 regulates the expression of the EGF receptor and its ligands via destabilization of oestrogen-related receptor alpha protein. British Journal of Pharmacology. 164(3) 1026-40

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