AF/LE Purified Anti-Mouse CD45.2 Monoclonal Antibody

AF/LE Purified Anti-Mouse CD45.2 Monoclonal Antibody

Catalog Number:
A001088249RED
Mfr. No.:
RD21519F
Price:
$300
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      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

      • Properties
        • Host
          mouse
          Antibody Type
          monoclonal
          Isotype
          IgG2a kappa
          Reactivity
          mouse
          Formulation
          0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/μg) as Determined by LAL gel clotting assay.
          Storage
          Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
          Concentration
          0.2 mg/mL
          Antigen
          Ly-5.2; LCA (Gene ID:19264; UniProt:P06800)

          * For research use only.

      • Applications
        • Application
          Block; Flow Cytometry; IHC

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