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Overview
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Specificity: Detects human Beta Amyloid. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Aducanumab.
Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL methodPlease contact us at for specific academic pricing.
Background
RUO Aducanumab is a human monoclonal antibody that selectively targets aggregated amyloid beta. In a transgenic mouse model of Alzheimer’s disease, aducanumab is shown to enter the brain, bind parenchymal amyloid beta, and reduce soluble and insoluble amyloid beta in a dose-dependent manner.
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