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Overview
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ACADL Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 421 amino acids (31-430) and having a molecular mass of 46.7 kDa. ACADL is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. ACADL is a homotetramer belonging to the acyl-CoA dehydrogenase family. ACADL takes part in the catabolism of fatty acids and amino acids and is a key source of energy for the heart and skeletal muscle. Mutation in the ACADL gene results in non-ketotic hypoglycemia and hypotonia (muscle weakness).
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Overview