ABCA1 Mouse Monoclonal Antibody

ABCA1 Mouse Monoclonal Antibody

Catalog Number:
A001448638ZEN
Mfr. No.:
Zen-222875
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      • Overview
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          Background

          The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in both alleles of this gene cause Tangier disease and familial high-density lipoprotein (HDL) deficiency.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG2a
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human ABCA1 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:19; UniProt:O95477)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          ICC/IF; FC
        • Application Dilutions
          IF 1/50-1/200
          FC 1/50-1/100

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