APC10 Mouse Monoclonal Antibody

APC10 Mouse Monoclonal Antibody

Catalog Number:
A001448639ZEN
Mfr. No.:
Zen-222046
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      • Overview
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          Background

          ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG1
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human ANAPC10 expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Molecular Weight
          Calculated MW: 22kDa;Observed MW: 22kDa
          Antigen
          (Gene ID:10393; UniProt:Q9UM13)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          WB; IHC-P; ICC/IF; FC; ELISA
        • Application Dilutions
          WB 1/500-1/1000
          IHC 1/100-1/200
          IF 1/50-1/200
          FC 1/50-1/100
          ELISA 1/10000

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